Department
of Pathobiology
Research
Areas:
Understanding the actions of intracellular lipid binding proteins: fatty acid binding proteins, sterol carrier proteins, and fatty acyl CoA binding proteins. Using biochemical, structural and molecular biological approaches, how these proteins affect lipid absorption and metabolism, and how they may serve as ligands for second messengers or activators for nuclear transcription factors. As well as in vitro studies, fat absorption, trafficking, and pathology are studied in genetically altered mice over expressing the respective proteins or in gene deleted mice in which these proteins are not expressed. Collaborative research: pathology of transgenic mice.
Understanding the actions of intracellular lipid binding proteins: fatty acid binding proteins, sterol carrier proteins, and fatty acyl CoA binding proteins. Using biochemical, structural and molecular biological approaches, how these proteins affect lipid absorption and metabolism, and how they may serve as ligands for second messengers or activators for nuclear transcription factors. As well as in vitro studies, fat absorption, trafficking, and pathology are studied in genetically altered mice over expressing the respective proteins or in gene deleted mice in which these proteins are not expressed. Collaborative research: pathology of transgenic mice.